Excerpt: And while the federal government has made efforts to try to bolster the stockpile of supplies, “there hasn’t been a lot of transparency. It’s hard to gauge the sufficiency of it,” said Jennifer B. Nuzzo, director of the Pandemic Center at the Brown University School of Public Health.
Guest essay by Jennifer Nuzzo, excerpt: How worried you should be about H5N1, the bird flu virus spreading on dairy farms in the United States, depends on whom you are.
The Centers for Disease Control and Prevention has described the current H5N1 risk to the general public as low. The risk that the virus poses is tempered by the fact that it doesn’t spread easily among people — yet.
Right now public-health experts have the difficult task of urging authorities who can do something about H5N1 to take action, while maintaining public trust. Americans have just been through a pandemic that resulted in over one million U.S. lives lost. They may feel weary of more bad news or fear-based messaging. Communicating that while the threat level for most people is low, but if nothing is done it could become quite high, is not easy but is important.
Excerpt: “The concern about H5N1 has always been there,” said Dr. Jennifer Nuzzo, professor of epidemiology and director of the Pandemic Center at the Brown University School of Public Health. “But in the last couple of years, [the virus] started doing things that have been a bit unusual.”
“We’ve seen this virus start to infect mammals and a wide range of mammals,” she said, pointing at the different outbreaks throughout the world. “That’s a concern because humans are mammals, and so mammals are more like us than birds are.”
But what makes this recent outbreak the most concerning for Nuzzo is that the virus is now capable of infecting cows. “Cows are mammals that humans have a lot more contact with than all the other mammals that we’ve seen get infected,” she said.
Excerpt: “My highest level of concern right now is for the workers on the farms, who we know are being exposed to this virus and we know are already getting sick with this virus,” said Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health. “We need to be talking more about protecting the workers who are in harm’s way today.”
Excerpt: Seth Berkley, a longtime and widely respected global health leader, said Thursday that it has been “shocking to watch the ineptitude” of the U.S. response to the avian influenza outbreak among dairy cattle, adding his voice to a chorus of critics.
In a presentation in London about vaccine development, Berkley, the former CEO of Gavi, the Vaccine Alliance, raised the issue of H5N1 bird flu when discussing whether the world was ready for another pandemic following its experience with Covid-19.
The Initiative's website collects hundreds of Pandemic Lamplighter stories and lessons learned from their innovation and ingenuity in the face of pandemic darkness
Opinion piece from Asa Hutchinson (fmr Governor of Arkansas) and Deval Patrick (fmr Governor of Massachusetts) on the American Democracy and Health Security Initiative.
Excerpt: “The Centre for Disease Control laboratory is one of a few labs where eye specimens can be tested for H5N1 – this needs to be fixed, easier access to eye swab testing is needed to protect and diagnose farm workers,” said Dr Jennifer Nuzzo, Director of the Pandemic Centre and Professor of Epidemiology at the Brown University on X (formerly Twitter).
Excerpt: Jennifer Nuzzo, director of the Pandemic Center at Brown University’s School of Public Health, said she wished other states were looking for H5N1 cases as aggressively as Michigan is.
“If there’s any takeaway from this finding it’s that this is probably the tip of the iceberg because this is the one state that we know of that has done the most in terms of testing on farms of both cows and also monitoring workers that are on the farms where they found cattle infections,” she told STAT.
Excerpt: Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health, said she was glad to hear that the CDC is pushing for continued flu surveillance.
“So many of our data points and response options are predicated on being able to find cases, and there are currently many holes in our ability to do that,” Nuzzo said.
Excerpt: “The more this virus circulates, the more there is a chance for mutations,” said Dr. Jennifer Nuzzo, a professor of epidemiology who directs the Pandemic Center at the Brown University School of Public Health. And more mutations could mean a bigger risk of the virus becoming highly infectious among more people.
Excerpt: “We have no idea if this virus is going to evolve to become a pandemic strain but we know today that farmworkers are being exposed and we have good reason to think that they are getting sick,” said Jennifer Nuzzo, director of the Pandemic Center at Brown University School of Public Health
Here & Now's Peter O'Dowd speaks with epidemiologist Jennifer Nuzzo about the bird flu that has recently sickened dairy cows in several states but so far only one dairy worker in Texas.
Professor Jennifer Nuzzo, epidemiologist and director of the Pandemic Center at the Brown University School of Public Health, joins host Megan Hall for a timely update on the recent outbreaks of H5N1 Bird Flu.
Excerpt: The discovery of bird flu virus particles in milk has moved the federal government to take more aggressive action to prevent the further spread of H5N1 on dairy farms. The Agriculture Department has rightly issued new testing recommendations meant to keep the virus from spreading across state lines. But this additional testing will do little to address the primary threat that H5N1 poses to humans: the infection of farmworkers. Our failure to protect them threatens their health and gives the virus an opportunity to evolve into a greater threat to people, including those who live far from dairy farms.
Excerpt: "It does feel like Ground Hog Day," said Jennifer Nuzzo, who heads Brown University's Pandemic Center. "We still seem to be stuck in reactive mode. We shouldn't be waiting for evidence that the virus is devastating us. We should be trying to act now to prevent the virus from devastating us."
Excerpt: But it's still not clear exactly where the flu virus has spread or what it's capable of, said several experts, including Jennifer Nuzzo, a professor of epidemiology and director of the Pandemic Center at the Brown University School of Public Health.
"Our surveillance is inadequate to know where this virus is and where it isn't, which is critical for protecting farmworkers and people involved in the dairy industry ‒ but also important for staying ahead of this virus to prevent a future pandemic," Nuzzo said.
Excerpt: “More testing is better,” said Jennifer Nuzzo, an epidemiologist and director of Brown University’s Pandemic Center. “But in many ways this policy is very leaky in terms of how much virus it will allow to move. And because we still don’t know what’s driving transmission between cows, we should not pin our hopes on this policy making a major dent in the infections we’re seeing.”
Excerpt: “Our job right now is to protect farmworkers,” said Jennifer Nuzzo, director of the Pandemic Center at Brown University School of Public Health. “We can’t do that unless we know where the virus is or where it isn’t.”
Excerpt: Some public health experts are concerned about how long that testing is taking — and the lack of transparency thus far about the government’s findings. Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health, questioned why the FDA did not immediately say it would test milk products and expeditiously culture any potential virus fragments found.
“Just from a government credibility standpoint, being transparent about what you’re doing, it’s important,” Nuzzo said.
Excerpt: To really understand the scale of spread as well as possible mechanisms of viral transmission, it’s necessary to conduct widespread testing of animals with and without symptoms, said Jennifer Nuzzo, an epidemiologist and director of Brown University’s Pandemic Center. “If we’re only testing cows with outward symptoms, we’re missing infections in those without.”
Excerpt: So let's start with the latest update, particles of this virus found in commercial pasteurized milk. How concerned should the everyday consumer be?
Dr. Jennifer Nuzzo, Brown University School of Public Health: I don't have any reason to be concerned at this point.
Finding evidence of genetic material, which is what the test results told us, by itself is not alarming. In order to know if the virus will infect us, we have to do a different kind of test. And this test was not that. They're actually undergoing those tests now.
But I don't have any reason to think that we will be harmed, because we use pasteurization. And I have no reason to think that the H5N1 virus is any different from all the other pathogens that we think could be in milk. Pasteurization doesn't remove the genetic material of those pathogens, but it changes the pathogens and either kills or it activates them, so that they can't infect us...
Excerpt: The Food and Drug Administration on Tuesday said it had been testing milk samples throughout the dairy production process and confirmed the detection of viral particles “in some of the samples,” but declined to provide details.
The presence of genetic fragments of the virus in milk is not unexpected. Pasteurization typically works to inactivate pathogens, said Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health. Pasteurization generally does not remove genetic material, but it typically renders pathogens unable to cause harm to people, Nuzzo said.
Excerpt: For decades, public health experts have warned of the danger of H5N1, also known as the avian flu, crossing over to humans. That fear became a reality when earliest this month, a dairy farm worker in Texas tested positive for the highly pathogenic avian influenza. This is the first reported cow-to-human spread of the virus. The U.S. has only ever recorded a handful of cases but there is mounting concern that mutations in the virus will allow it to spread to more mammals and possibly, more people. Are we ready for an influenza pandemic of this kind? Joining us today on AirTalk to talk about this latest outbreak and the threat it poses to humans is Jennifer Nuzzo, Professor of Epidemiology and Director of the Pandemic Center at Brown University.
Excerpt: For a virus to have pandemic potential, it needs to be able to pass easily from person-to-person. H5N1 does not have the ability to do so, but scientists fear it could develop this feature.
“The bigger picture is that this virus is not cooling off,” CFR Senior Fellow Jennifer Nuzzo told Politico. “We’ve been worrying about this virus for twenty years, more than twenty years. And in the last year, it has really been remarkable in how far across the globe it has been spreading, and how many species it’s been affecting.”
Excerpt: “The bigger picture is that this virus is not cooling off,” said Jennifer Nuzzo, director of the Pandemic Center at the Brown University School of Public Health. “We’ve been worrying about this virus for 20 years, more than 20 years. And in the last year, it has really been remarkable in how far across the globe it has been spreading, and how many species it’s been affecting.”
Excerpt: "I worry a little bit that the perceived speed with which we were able to develop safe and effective vaccines has given people unrealistic expectations," said Jennifer Nuzzo, director of the Pandemic Center at Brown University School of Public Health. "Nevertheless, we did something remarkable, and we proved to ourselves that we can do hard things," she added.
A new exercise, highlighting the ability of Artificial Intelligence (AI) to meet pandemic threats, will be tested this week at the Munich Security Conference.
Excerpt: If this change takes place, it shouldn't be interpreted to mean that COVID-19 is less contagious, says Jennifer Nuzzo, an epidemiologist and director of the Pandemic Center at Brown University School of Public Health.
"The science of COVID has not changed," Nuzzo says. If you test positive for COVID-19, you're likely contagious for a few days at least and risk spreading the coronavirus to others.
Excerpt: The proposed recommendations also seem not to take into account older Americans, or those who are immunocompromised or otherwise at risk of severe outcomes from Covid, said Jennifer Nuzzo, director of the Pandemic Center at Brown University School of Public Health.
Dr. Nuzzo said she has an aunt with cancer who had twice contracted Covid in a health care facility. “I do feel for people who now feel even less protected,” she said.
At the very least, the C.D.C. should advise that people who end isolation after one fever-free day also wear N95 masks or the equivalent when leaving their homes, she added.
The second installment of the Pandemic Center’s “Our Storied Health” series highlights environmental injustice in the American South, and explores the potential of storytelling to advance public health.
Article by Pandemic Center Director Jennifer Nuzzo: It’s been just over six months since physician Mandy Cohen took the helm of the U.S. Centers for Disease Control and Prevention (CDC), emphasizing that making the agency more transparent is essential for rebuilding the public’s trust in our national health agency. To achieve this, the CDC must get better at sharing data with the public.
A newly opened Washington base for the Pandemic Center at Brown’s School of Public Health will expand impact and connect current and future public health leaders with national and global policymakers.
Excerpt: Jennifer B. Nuzzo, DrPH, director of the Pandemic Center at Brown University School of Public Health: Here's what I haven't seen that I would like to see ... I would like to see a bipartisan commitment to have a serious assessment of what went wrong during the pandemic. We need to get to the bottom of this in the same way that we wanted to get to the bottom of what went wrong during 9/11. A number of the United States’ challenges were probably as much about government effectiveness as they were about lack of resources, money, etc. We need to really, truly have an audit. Not necessarily in a punitive way, but a true audit.
Excerpt: Herd immunity provided a temporary reprieve, but it also created a new problem. A lower incidence of Zika meant less commercial interest in making a vaccine, because the market for a Zika vaccine would by definition be smaller. Vaccine companies also struggled to find populations in which to test a vaccine, because too few people now had confirmed Zika infections. "The general momentum that was behind the development of a Zika vaccine ground to a halt," says Jennifer Nuzzo, the director of the Pandemic Center at Brown University.
The Advance Warning and Response Exemplars (AWARE) project will identify positive outliers in successful early warning and response to significant public health events, including outbreaks of pathogens of pandemic potential as well as climate-sensitive infectious diseases
Article by Pandemic Center Senior Advisor Wilmot James:
One of two freshly recruited lecturers from the University of Stellenbosch who joined the University of the Western Cape in the early 1970s, Janis Grobbelaar was a person of Afrikaner background who walked a very different path.
Excerpt: A major effort is under way to put a resolution before the next World Health Organisation (WHO) assembly, scheduled for May 27-June 1 2024, to advance a strategic dialogue about establishing globally applicable norms, standards and protocols for biosafety, biosecurity and biosurveillance in the age of genetic engineering.
This week in Cape Town the annual conference of the African Society for Laboratory Medicine (ASLM) is meeting to discuss the challenge of advancing scientific work on disease-causing pathogens while ensuring this is done safely and securely in properly equipped laboratories. There is considerable momentum in the post-Covid world to put guardrails in place to ensure genetic engineering stays in its lane while not stifling the great benefits of science applications to advance health.