(Airdate 10/29/2025) In this episode, Jess and Sarah welcome Dr. Seth Berkley, a leading public health expert, to examine pressing global health security challenges. The scientists explore the concerning resurgence of preventable diseases and the critical role of vaccination programs in protecting populations. Dr. Berkley shares insights on lessons learned from the COVID-19 pandemic, addressing persistent issues of vaccine inequity and hesitancy across different communities. The conversation tackles the troubling rise of anti-science legislation and the erosion of public trust in scientific institutions, while also examining the tensions between individual health freedom and collective public health responsibility. Throughout the episode, the experts offer both sobering assessments of current challenges and hopeful perspectives on future advancements in global health and scientific progress.

Seth Berkley, MD, an infectious disease epidemiologist currently advising vaccine, biotechnology, and technology companies; an adjunct professor and senior adviser to the Pandemic Center at Brown University; former CEO of Gavi, the Vaccine Alliance; cofounded COVAX; founded and served as CEO of the International AIDS Vaccine Initiative; and the author of Fair Doses: An Insider’s Story of the Pandemic and the Global Fight for Vaccine Equity (University of California Press, 2025), talks about the need for vaccine equity and lessons learned (and ignored) from the COVID pandemic.

At the World Health Summit in Berlin earlier this month, I was pleased to hear discussions highlighting the crucial role of health initiatives in overall global security.

This is hardly a new topic, but it’s increasingly relevant. The risks from natural, accidental, and deliberate spread of infectious agents are escalating and with advances in synthetic biology and artificial intelligence, outbreaks have the potential to be far more lethal. Strong, well-functioning health systems that improve people’s health and help prevent outbreaks of emerging new infectious diseases are as vital to global security as advanced weaponry, military strategy, and intelligence.

Months before COVID-19 was declared a pandemic, efforts were already underway to ensure low-income countries would get access to future vaccines against the infection. The book "Fair Doses" tells that story and discusses the ongoing fight for vaccine equity around the world.

The former head of the international vaccine access organisation Gavi tells The BMJ about the politicising of vaccination, chaos at the CDC, and the impact on global vaccine equity

Epidemiologist Dr. Seth Berkley spoke to Live Science about the importance of vaccine equity and the obstacles undermining it, as well as the political challenges to vaccines being raised in the U.S.

AI experts, Nobel Laureates, Fortune 500 CEOs, NGO leaders and leading academic gathered in Mexico to discuss how to intervene in a system to keep superintelligence safe without sacrificing the core values of a free and open society.

During the past few months, President Trump and his health secretary, Robert F. Kennedy, Jr., have made sweeping, thinly evidenced claims that Tylenol (acetaminophen) in pregnancy is linked to autism and that SSRIs (antidepressants) might be linked to fetal damage. In the case of Tylenol, the few research studies that claim to find a link either don’t control for confounding variables or find that the link disappears when they do; the drug has also been safely prescribed to children for decades. And scientists actually have studied SSRIs in pregnancy fairly extensively. But while these two types of drugs have been widely studied, that’s more the exception than the norm. In fact, most clinical trials and drug studies explicitly exclude people who are pregnant.

Multilateral initiatives are needed to signal confidence and fill funding gaps in mRNA research, writes Jennifer B Nuzzo

In this episode Ben Plumley catches up with Dr. Seth Berkley, founder of the International AIDS Vaccine Initiative, former CEO of GAVI and amongst other responsibilities, now a senior advisor at Brown University's School of Public Health's Pandemic Center. Seth has recently published a new book “Fair Doses: An Insider's Story of the Pandemic and the Global Fight for Vaccine Equity” and he and Ben discuss the book’s topics of vaccine equity, misinformation, and the rapid innovations in vaccine development, particularly the success and future potential of mRNA vaccines. Dr. Berkley highlights the challenges posed by misinformation and the political landscape, as well as the importance of global collaboration in addressing pandemics. They also explore his defining role in Covax's efforts to distribute COVID vaccines, the need for local manufacturing, and the impacts of nationalistic policies on global health. Dr. Berkley stresses the critical role of ongoing innovation and funding in preparing for future health crises and ensuring equitable access to health technologies. And he pulls no punches on the current US administration’s failures in supporting global health research and partnerships.

Avian flu flared up in Minnesota poultry operations last month after a nearly eight-month reprieve, forcing farmers to depopulate eight turkey barns.

A vaccine exists for this highly pathogenic avian influenza, which could be used against the nearly four-year outbreak that has wiped out 9.2 million birds in Minnesota alone.