When the world was in a health crisis, Dr. Seth Berkley didn’t just watch—he was at the centre of the storm. In this episode of the Public Health Insight Podcast, we rewind to his early days and trace his path through global health’s toughest challenges.
The idea was born over drinks at the Hard Rock Hotel in Davos Switzerland, on January 23, 2020.
There was a new virus ringing alarm bells in China, but it hadn't yet become an international concern. It didn't even have a name. Yet Seth Berkley was already thinking about how to protect the world with vaccines against it.
Berkley was the CEO of Gavi, the Vaccine Alliance, a nonprofit group dedicated to expanding access to vaccines around the globe.
Canada is no longer measles-free because of ongoing outbreaks, international health experts said Monday, as childhood vaccination rates fall and the highly contagious virus spreads across North and South America.
The loss of the country’s measles elimination status comes more than a year after the highly contagious virus started spreading.
Measles cases in the U.S. and Canada continue to rise, but not as dramatically as they did. Vaccination is still the best way to protect your family and those around you who cannot be vaccinated.
(Note – we use data from both the CDC and the Brown University Pandemic Center’s weekly tracking report. While the CDC tracks confirmed cases only, the Pandemic Center tracks both probable and confirmed cases using publicly available data from state health departments. Numbers below are correct as of 11/6).
So, how many cases and outbreaks of measles are there in the US at the moment?
It’s Election Day in parts of the country, so we thought it was time to talk politics.
Dr. Craig Spencer, from Brown University’s School of Public Health, penned a Substack last week that stopped us cold. In it, he makes a bold case that public health needs to get more political—not partisan, but political in the sense of organizing, mobilizing, and demanding what people say they value: cleaner air, safer food, prevention that actually gets funded.
It’s a striking call at a moment of profound change — what some call a reimagining, others a dismantling — of public health itself. But if you look at the polling across Republicans, Democrats, and the MAHA “curious,” there’s surprising common ground right in public health’s wheelhouse.
It’s time, Spencer argues, for public health to step into the political arena to fight for change or watch the system unravel.
Walgreens is unveiling an expanded tracker of flu and COVID-19 to monitor where they're spreading across the country this winter, the company shared first with Axios.
Why it matters: Commercial and academic tools are becoming more important for identifying respiratory virus hotspots this year as federal data becomes less available.
Driving the news: Walgreens is adding COVID-19 data to its existing flu prevalence tracker to create a more comprehensive picture of when and where respiratory viruses are spiking this winter, the company told Axios on Monday.
Florida’s announcement that it would scrap public school vaccine mandates next year hit Elizabeth particularly hard. Her 11-year-old daughter suffers from a rare immunodeficiency disorder that requires biweekly plasma infusions to provide some protection against disease.
But she can still be out of school for 50 days during the school year — and Elizabeth is worried that falling vaccine rates will make their situation far worse.
Amid massive cutbacks to health funding, Seth Berkley says that global health organizations face a “devil’s choice” around vaccines. They can focus on bringing much-needed immunizations to people now or get ready for the next pandemic. And it’s coming.
Global health expert Seth Berkley stated that future outbreaks and pandemics are inevitable, with the potential to be more severe than COVID-19. Berkley emphasized the certainty of such events due to evolutionary factors during a recent discussion on global health preparedness. He highlighted the importance of learning from the COVID-19 pandemic to better prepare for future health crises.
Measles, whooping cough, and other vaccine-preventable diseases are on the rise around the world, and cuts to foreign aid, coupled with growing vaccine hesitancy, and persistent gaps in vaccine access are fueling outbreaks in poor and wealthy nations alike. Global health experts discuss the drivers of these outbreaks, the solutions that can advance vaccine equity and better public health worldwide, and a new vaccine-preventable disease tracker from Think Global Health, developed in collaboration with ProMED.
(Airdate 10/29/2025) In this episode, Jess and Sarah welcome Dr. Seth Berkley, a leading public health expert, to examine pressing global health security challenges. The scientists explore the concerning resurgence of preventable diseases and the critical role of vaccination programs in protecting populations. Dr. Berkley shares insights on lessons learned from the COVID-19 pandemic, addressing persistent issues of vaccine inequity and hesitancy across different communities. The conversation tackles the troubling rise of anti-science legislation and the erosion of public trust in scientific institutions, while also examining the tensions between individual health freedom and collective public health responsibility. Throughout the episode, the experts offer both sobering assessments of current challenges and hopeful perspectives on future advancements in global health and scientific progress.
Seth Berkley, MD, an infectious disease epidemiologist currently advising vaccine, biotechnology, and technology companies; an adjunct professor and senior adviser to the Pandemic Center at Brown University; former CEO of Gavi, the Vaccine Alliance; cofounded COVAX; founded and served as CEO of the International AIDS Vaccine Initiative; and the author of Fair Doses: An Insider’s Story of the Pandemic and the Global Fight for Vaccine Equity (University of California Press, 2025), talks about the need for vaccine equity and lessons learned (and ignored) from the COVID pandemic.
At the World Health Summit in Berlin earlier this month, I was pleased to hear discussions highlighting the crucial role of health initiatives in overall global security.
This is hardly a new topic, but it’s increasingly relevant. The risks from natural, accidental, and deliberate spread of infectious agents are escalating and with advances in synthetic biology and artificial intelligence, outbreaks have the potential to be far more lethal. Strong, well-functioning health systems that improve people’s health and help prevent outbreaks of emerging new infectious diseases are as vital to global security as advanced weaponry, military strategy, and intelligence.
Months before COVID-19 was declared a pandemic, efforts were already underway to ensure low-income countries would get access to future vaccines against the infection. The book "Fair Doses" tells that story and discusses the ongoing fight for vaccine equity around the world.
The former head of the international vaccine access organisation Gavi tells The BMJ about the politicising of vaccination, chaos at the CDC, and the impact on global vaccine equity
Epidemiologist Dr. Seth Berkley spoke to Live Science about the importance of vaccine equity and the obstacles undermining it, as well as the political challenges to vaccines being raised in the U.S.
With measles spreading and long-trusted sources of public health information falling short, Professor Jennifer Nuzzo breaks down the outbreak, the state of public health communications and the Pandemic Center’s tracking report, which publishes key infectious disease data every week.
AI experts, Nobel Laureates, Fortune 500 CEOs, NGO leaders and leading academic gathered in Mexico to discuss how to intervene in a system to keep superintelligence safe without sacrificing the core values of a free and open society.
During the past few months, President Trump and his health secretary, Robert F. Kennedy, Jr., have made sweeping, thinly evidenced claims that Tylenol (acetaminophen) in pregnancy is linked to autism and that SSRIs (antidepressants) might be linked to fetal damage. In the case of Tylenol, the few research studies that claim to find a link either don’t control for confounding variables or find that the link disappears when they do; the drug has also been safely prescribed to children for decades. And scientists actually have studied SSRIs in pregnancy fairly extensively. But while these two types of drugs have been widely studied, that’s more the exception than the norm. In fact, most clinical trials and drug studies explicitly exclude people who are pregnant.
Measles has been declared eliminated in the U.S. for 25 years, but a surge in cases is threatening that status. Jennifer Nuzzo, director of the Pandemic Center at Brown University, joined Humans in Public Health to break down the outbreak, the chaotic federal response and how her team's tracker is stepping in to provide reliable, life-saving data.
In this episode Ben Plumley catches up with Dr. Seth Berkley, founder of the International AIDS Vaccine Initiative, former CEO of GAVI and amongst other responsibilities, now a senior advisor at Brown University's School of Public Health's Pandemic Center. Seth has recently published a new book “Fair Doses: An Insider's Story of the Pandemic and the Global Fight for Vaccine Equity” and he and Ben discuss the book’s topics of vaccine equity, misinformation, and the rapid innovations in vaccine development, particularly the success and future potential of mRNA vaccines. Dr. Berkley highlights the challenges posed by misinformation and the political landscape, as well as the importance of global collaboration in addressing pandemics. They also explore his defining role in Covax's efforts to distribute COVID vaccines, the need for local manufacturing, and the impacts of nationalistic policies on global health. Dr. Berkley stresses the critical role of ongoing innovation and funding in preparing for future health crises and ensuring equitable access to health technologies. And he pulls no punches on the current US administration’s failures in supporting global health research and partnerships.
Avian flu flared up in Minnesota poultry operations last month after a nearly eight-month reprieve, forcing farmers to depopulate eight turkey barns.
A vaccine exists for this highly pathogenic avian influenza, which could be used against the nearly four-year outbreak that has wiped out 9.2 million birds in Minnesota alone.
Vietnam is among the countries most affected by extreme weather, which fuels the spread of infectious diseases. Prolonged heat and humidity create ideal conditions for mosquitoes to breed, driving dengue and other vector-borne illnesses. Flooding, meanwhile, increases exposure to waterborne and digestive diseases. Together, these climate-sensitive risks underline the urgent need for early warning and response systems to protect public health.
As a number of federal policies impact availability of COVID-19 vaccines, Rhode Island is looking to preserve access through protective measures. The moves followed a recent U.S. Food and Drug Administration green-light of three new COVID-19 vaccines.
But in approving these vaccines, the FDA also restricted their use to people who are 65 years or older or have underlying health conditions. Those who are not eligible to receive the vaccine can get a prescription from a health care professional, but they must pay out of pocket prices.
Florida State Surgeon General Dr. Joseph Ladapo announced that The Sunshine State will become the first in the nation to remove the mandatory vaccination mandate for schoolchildren. That means that by the end of 2025, kids entering public school will no longer be required to have vaccinations for contagious diseases such as Chicken Pox, Hepatitis B among others. While Dr. Ladapo says the decision will ultimately give power back to individuals are parents to decide what they put in their children’s bodies, other medial professional disagree with the decision and say a health crisis could be looming. Former Florida Surgeon General and Professor of Education at Brown University’s School of Public Health, Dr. Scott Rivkees, sat with us to talk about the ramifications that could come, not just with kids, but with public health as well.
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Welcome to “the last bite,” an end-of-week food and ag roundup from the Minnesota Star Tribune. Reach out to business reporter Brooks Johnson at brooks.johnson@startribune.com to share your news and favorite gas station food.
General Mills will be without a chief marketing officer for a time, as Doug Martin has taken the same position at a different food-ish company.
Martin is now heading up the marketing department at Wawa, a gas station chain that is pretty much the Kwik Trip of the East Coast, with a similar cult-like following thanks to its counter-serve food.
Among its many painful lessons, the COVID-19 pandemic taught us that America’s defenses against a devastating health crisis were far weaker than most had reason to expect. More than 1.2 million Americans lost their lives to COVID, the most of any country. It’s puzzling and frightening to watch the Trump Administration dismantle initiatives aimed at keeping us safe from another pandemic.
And let’s not kid ourselves; another pandemic is evolutionarily inevitable. We can’t say when it will strike or if it will be worse than COVID. (Deadly as it was, COVID proved to be far less fatal than others we’ve seen recently, like Ebola, Marburg, MERS and SARS.) But research has projected that there is about a 50 percent chance another COVID-like magnitude of a pandemic (>25 million global deaths) will hit us in the next 20 to 25 years.
EAST PROVIDENCE, R.I. (WPRI) — Earlier this week, President Donald Trump indicated that using acetaminophen, commonly known by its brand name Tylenol, shouldn’t be used during a pregnancy and could contribute to rising autism rates in the United States.
The claim has since been scrutinized by health officials, while also shedding light on how clinical data about pregnant women is gathered.
Alyssa Bilinski, a researcher at Brown University, joined 12 News at 4 on Wednesday to discuss Trump’s claim and the risks of medication in pregnant women.
The Pandemic Agreement, adopted by the World Health Assembly in May, is a historic step toward strengthening global systems to prevent, detect, and respond to epidemic and pandemic threats. Yet many low- and middle-income countries face significant political and technical challenges in ratifying and implementing the agreement.
No country is fully prepared for a future pandemic or epidemic. National implementation of the Pandemic Agreement will require sustained political will, policy reforms, investments in capacity building, and ongoing transparency, monitoring, and accountability.
GAINESVILLE, Fla. (WCJB) - Children in Florida are required to get several vaccines before they begin school. It’s a requirement supported by Dr. Scott Rivkees.
“Schools should be places where children should be able to go to without having to worry about getting vaccine preventable diseases,” he told TV20.
He was the state’s former surgeon general during Gov. Ron DeSantis’ first term and helped lead the state during the start of COVID-19.
Rivkees is now a professor at Brown University, but is sounding off on the state’s plan to eliminate vaccines mandates for children. It’s a decision made earlier this month by Dr. Joseph Ladapo, the man who replaced Rivkees who left his post in 2021.
On Monday, President Trump, flanked by the heads of the National Institutes of Health and the Food and Drug Administration, drew a clear link between autism and pregnant women’s use of acetaminophen, the active ingredient in Tylenol. He urged women to avoid the drug while pregnant unless “absolutely necessary,” claiming, “There’s no downside in not taking it.”
The White House pointed to a recent systematic review of 46 studies, in which authors urged caution in using the medication, recommending only “judicious acetaminophen use” following “medical consultation.” At the same time, many experts are stating the opposite. For example, a statement from the American College of Obstetricians and Gynecologists emphasized that pregnant patients “should not be frightened away from the many benefits of acetaminophen.”
Before he set foot in 200 Independence Avenue, Washington DC, Robert F Kennedy Jr, US president Donald Trump’s secretary of health and human services, had raised more than a few eyebrows from America’s medical establishment. Around 17,000, to be precise – that’s how many doctors signed a letter from the Committee to Protect Health Care urging senators to reject his nomination, saying he was “unqualified to lead” and was “actively dangerous”.
Their petition failed. Today, Kennedy Jr, better known as RFK, is head of an agency with an almost two trillion-dollar budget and a little over 80,000 employees. On Monday, speaking from the White House, Trump and the US secretary of health and human services said women should not take acetaminophen, also known by the brand name Tylenol, “during the entire pregnancy.” It was announced that the Food and Drug Administration would begin notifying doctors that the use of acetaminophen “can be associated” with an increased risk of autism, but neither Trump or Kennedy Jr provided any peer reviewed medical evidence to support this. They also raised unfounded concerns about vaccines contributing to rising rates of autism.
President Trump tied the use of acetaminophen during pregnancy to autism and made several other claims about vaccines. William Brangham discussed those claims and the concerns about what the president said with Alycia Halladay of the Autism Science Foundation and Jennifer Nuzzo of Brown University’s School of Public Health.
The committee that offers vaccine advice to the nation’s top public health agency voted Friday against recommending the updated COVID-19 vaccine to people aged 6 months or older, instead leaving the decision to individuals. The panel also decided against recommending that states and local authorities require a prescription for COVID-19 vaccines.
On many levels, people watching the two-day proceedings of the Advisory Committee on Immunization Practices (ACIP) did not know what to expect. Much of the week was uncharted, and a planned vote on the hepatitis B vaccine was tabled despite being on the agenda.
(TNND) — The panel that develops vaccine recommendations for the Centers for Disease Control and Prevention proposed one change to childhood immunizations but tabled a vote for another before turning their attention to the hotly debated COVID-19 vaccines.
The Advisory Committee on Immunization Practices continued its two-day meeting Friday after voting Thursday to recommend a standalone chickenpox vaccination in toddlers to reduce their risk of febrile seizures.
A combination MMRV vaccine is available, which includes measles, mumps, rubella and varicella (chickenpox) immunizations.
In April 2023, Robert F. Kennedy Jr. announced his presidential bid in Boston, promising to “Make America Healthy Again.” Since becoming President Trump’s secretary of Health and Human Services, Kennedy has made a mockery of this promise, undermining decades of public health consensus.
His tenure recently reached its lowest point, with the explosive departure of Director Susan Monarez from the Centers for Disease Control and Prevention. Four other officials left the CDC over Kennedy’s leadership, with one accusing him of “weaponization of public health.”
The Trump administration’s response to the Ebola outbreak in the Democratic Republic of Congo doesn’t appear to be following the playbook used in previous outbreaks, and it’s sounding alarm bells among biosecurity experts.
Current and former leaders of the U.S.’s infectious disease response apparatus are warning that they’re not seeing the level of coordination between federal agencies that’s needed to successfully respond to such outbreaks abroad.
The world’s market for vaccines, as it exists today, depends on the United States. The U.S. has poured immense resources into the design and development of vaccines, and has paid far higher prices for doses than most other nations can afford. The federal government has issued broad vaccine recommendations, generating strong, consistent demand. “That’s a predictable market,” Richard Hughes IV, a public-health-law expert and the former vice president of public policy at Moderna, told me. It’s also a huge one. Seth Berkley, the former CEO of Gavi, which supports the immunization of about half the world’s children, told me that the U.S. accounts for 35 to 40 percent of global vaccine revenue at a minimum, more than all of Europe combined.
Americans across the political spectrum are aligned on at least one belief, albeit for different reasons: The CDC is a mess. In a poll conducted this summer by The Washington Post and KFF, a nonpartisan health-policy organization, Democrats and Republicans alike expressed low confidence that the agency could be trusted to make independent decisions based on scientific fact. Robert F. Kennedy Jr., as the head of Health and Human Services, has described the CDC as dysfunctional and politicized; according to the former CDC director Susan Monarez, he has also disparaged the agency’s workers as child murderers. Meanwhile, public-health experts—a group that has historically worked in tandem with the CDC—now question the agency’s credibility with Kennedy in charge. “You can’t trust anything that comes out of the CDC,” Michael Osterholm, who directs the University of Minnesota’s Center for Infectious Disease Research and Policy, told me.
David Baltimore explained to Mr Mandela, in a language so precise as only he could, that there was no vaccine for Aids and that an aggressive rollout of antiretrovirals, tough management of needlestick use and a high visibility public campaign for safe sex were key.
On Sunday, after four days of silence about how Ladapo’s all-encompassing goal would be achieved, the health department issued a statement saying it was proposing a rule change “to remove requirements for childhood immunizations … not required for school entry” such as hepatitis B, varicella (chickenpox), and influenza.
Vaccine requirements for polio, diphtheria, measles, whooping cough, mumps and tetanus, it said, “remain in place, unless updated through legislation”, and “all vaccines will remain available to families throughout Florida”.
Scott Rivkees, an infectious diseases expert at Brown University and former Florida surgeon general under DeSantis, told the Guardian it appeared Ladapo was in retreat.
An artificial intelligence tool out of Boston University aims to enhance surveillance of disease outbreaks across the globe, a task traditionally informed by several federal agencies that have been dismantled or cut back in the second Trump administration.
The project known as the Biothreats Emergence, Analysis and Communications Network, or BEACON, took more than a year to develop. It launched in April, as the Trump administration slashed the workforce and budget at the Centers for Disease Control and Prevention, all but eliminated the U.S. Agency for International Development and cut ties to the World Health Organization.
Vaccines have been making a lot of headlines over the last five years. First, because of the remarkable speed with which the Covid vaccine was developed, and more recently, because of the Trump administration’s hostility to vaccines. I can’t think of a better time to have a conversation with today’s guest, Seth Berkley, who for more than a decade ran the largest vaccination program in the world.
Public health in America is undergoing dramatic changes, from changing access to vaccines to defunding research into treatment and prevention of diseases. This is all the work of the second Trump administration, more specifically, the leadership of Health and Human Services Secretary Robert F. Kennedy Junior and it’s having effects beyond America.
In recent years, the U.S. has played a major role in battling malaria, providing more than a billion dollars annually to fight it. That is, until this year, when the Trump administration froze foreign aid.
The effects of that are covered in a recent article from the publication Science. Public health experts weigh in on that and the broader changes in public health in America.
To protect the people of Massachusetts from deadly bird flu in the U.S., the state’s health director, Robert Goldstein, is relying on an artificial intelligence platform that reads newspapers for outbreak information. It also searches for signals of outbreaks of other deadly diseases, such as Ebola, that are farther away. Those data used to come from the World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention. But with the U.S. withdrawing from the former and cutting thousands of jobs from the latter, Goldstein is trying to fill huge gaps in any way he can. The AI platform in Massachusetts, called BEACON, scans news reports in local languages and draws on a network of outbreak analysts from around the world, searching for early signs of looming disease threats.
When Health Secretary Robert F. Kennedy Jr. defended his vision of the Centers for Disease Control and Prevention in a recent op-ed, he cited one of the agency’s biosurveillance programs as a prime example of the agency’s capabilities: the Biothreat Radar Detection System.
But the “Biothreat Radar Detection System” doesn’t appear to exist — at least, not yet, sources inside and outside the CDC told NOTUS. And new details about how the program might apply AI to biosurveillance are giving biosecurity experts some pause.
Earlier this week, Florida Surgeon General Joseph Ladapo, with Gov. Ron DeSantis at his side, likened childhood vaccines to slavery and recommended that requirements for childhood vaccination be eliminated. Children in Florida will now be more at risk of vaccine-preventable illnesses than at any time in recent history, but the move will also have an impact in the broader population.